Drug hypersensitivity reactions and allergy in patients with mastocytosis
نویسندگان
چکیده
منابع مشابه
the past hospitalization and its association with suicide attempts and ideation in patients with mdd and comparison with bmd (depressed type) group
چکیده ندارد.
In vitro tests for drug hypersensitivity reactions: an ENDA/EAACI Drug Allergy Interest Group position paper.
Drug hypersensitivity reactions (DHRs) are a matter of great concern, both for outpatient and in hospital care. The evaluation of these patients is complex, because in vivo tests have a suboptimal sensitivity and can be time-consuming, expensive and potentially risky, especially drug provocation tests. There are several currently available in vitro methods that can be classified into two main g...
متن کاملDrug-specific in vitro release of IFN-gamma in patients with delayed cutaneuos drug hypersensitivity reactions
Method A total of 16 patients with clinically well-established maculopapular exanthema due to antiepileptic drugs hypersensitivity in remission state and 15 drug-exposed control donors without DHR were included to the study. Peripheral blood mononuclear cells of investigated individuals were isolated and cultured under defined conditions with drugs. IFN-gamma production was measured with electr...
متن کاملAllergic hypersensitivity to cannabis in patients with allergy and illicit drug users.
BACKGROUND Cannabis is the illicit drug most widely used by young people in high-income countries. Allergy symptoms have only occasionally been reported as one of the adverse health effects of cannabis use. OBJECTIVES To study IgE-mediated response to cannabis in drug users, atopic patients, and healthy controls. METHODS Asthmatic patients sensitised to pollen, and all patients sensitised t...
متن کاملDrug hypersensitivity reactions: pathomechanism and clinical symptoms.
Small molecules, used as drugs, can induce immune reactions by binding covalently as haptens to a carrier protein, which is thereby modified and immunogenic. In addition, drugs bind to proteins via hydrogen bonds, electrostatic force, and van der Waals forces, and may directly interact with immune receptors such as T cell receptors or major histocompatibility complex molecules (pharmacologic in...
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ژورنال
عنوان ژورنال: Dermatology Review
سال: 2017
ISSN: 0033-2526
DOI: 10.5114/dr.2017.66219